TALKE LAB ACTIVE PROJECTS
INTRAOCULAR PRESSURE SENSOR
Glaucoma is one of the leading causes of irreversible blindness that affect millions of people worldwide. Eye pressure is associated optic nerve damage and known to be the number one risk factor for glaucoma. Since 2013, the Talke Lab has been developing a novel optical pressure sensor that enables long term and frequent intraocular pressure (IOP) monitoring in order to improve patient care and treatment.
ESOPHAGEAL DEFLECTION DEVICE
An esophageal deflection device is being developed to assist cardiologists who perform left atrium catheter ablation procedures for atrial fibrillation patients. As the heart tissue is thermally ablated, it is possible the esophagus is damaged while it presses up against the heart. The device consists of an inherently deflected overtube and relatively stiff insertion piece. A cardiologist will insert the fully assembled device and simply pull the insertion piece to deflect the over tube and esophagus away from the heart.
BIOFILM RETARDENT CATHETER
Catheter acquired urinary tract infection (CAUTI) is a significant problem in the medical community. Our work involves the design and investigation of a passive electricidal urinary catheter coating. Composite films are prepared by combining a thermoset elastomer with active materials zinc, silver, and/or silver (I) oxide powders. Methods used to quantify composite films’ ability to generate hydrogen peroxide, electric potentials, changes in pH, and inhibit planktonic bacteria and biofilm synthetic urine are studied.
To intubate a patient successfully, a physician needs to insert an endotracheal tube (ETT) into the patient’s mouth and secure it in the airway. A delay in securing the ETT into position of greater than 4 minutes can result in permanent brain injury or death of the patient. Our research aims to fill a critical gap by development of a detachable bronchoscope that functions as both as an ETT exchanger and an bronchoscope reducing the time needed to replace an ETT and guaranteeing proper ETT position within the airway.
In this project, we develop a portable 2-in-1 internet-enabled device capable of performing slit lamp examination and visual acuity screening. The slit lamp portion of the instrument can automate the screening process of the eye anterior segment by generating a high-intensity narrow slit of white light with a fixed width, and sweep this slit beam across the eye for a full bio-microscopy exam.